LONDON — Britain will reduce its aid sent to Africa by more than half, as the government unveils the impact of steep cuts to development assistance for countries across the world. On Thursday the Foreign Office revealed the next three years of its overseas development spending, giving MPs and the public the first look at the impact of Labour’s decision to gut Britain’s aid budget in order to fund an increase in defense spending. Government figures show that the value of Britain’s programs in Africa will fall by 56 percent from the £1.5 billion in 2024/25 when Labour took office to £677 million in 2028/9. It follows the move to reduce aid spending from 0.5 to 0.3 percent of gross national income. However, the government did not release the details of the funding for specific countries, giving Britain’s ambassadors and diplomats time to deliver the news personally to their counterparts across the world ahead of any potential backlash from allies. Foreign Secretary Yvette Cooper told MPs that affected countries want Britain “to be an investor, not just a donor” and “want to attract finance, not be dependent on aid,” as she pointed to money her department had committed to development banks and funds which will help Africa raise money. The decision shows a substantial shift in the government’s focus, moving away from direct assistance for countries, and funneling much of the remaining money into international organizations and private finance initiatives. Chi Onwurah, chair of the All Party Parliamentary Group for Africa, told POLITICO that she was “dismayed at the level and extent of the cuts to investment in Africa and the impact it will have particularly on health and economic development.” She added: “I hope the government recognizes that security of the British people is not increased by insecurity in Africa and increased migration from Africa, quite the opposite.” Ian Mitchell from the Center for Global Development think tank noted the move was “a remarkable step back from Africa by the U.K.” NEW PRIORITIES Announcing the cuts in the House of Commons, Cooper stressed that the decision to reduce the aid budget had been “hugely difficult,” pointing to similar moves by allies such as France and Germany following the U.S. President Donald Trump’s decision to dramatically shrink America’s aid programs after taking office in January 2025. She insisted that it was still “part of our moral purpose” to tackle global disease and hunger, reiterating Labour’s ambition to work towards “a world free from extreme poverty on a livable planet.” Cooper set out three new priorities for Britain’s remaining budget: funding for unstable countries with conflict and humanitarian disasters, funneling money into “proven” global partnerships such as vaccine organizations, and a focus on women and girls, pledging that these will be at the core of 90 percent of Britain’s bilateral aid programs by 2030. A box with the Ukrainian flag on it awaits collection in Peterborough, U.K. on March 10, 2022. | Martin Pope/Getty Images Only three recipients will see their aid spending fully protected: Ukraine, the Palestinian territories and Sudan. Lebanon will also see its funding protected for another year. All bilateral funding for G20 countries will end. Despite the government’s stated priorities, the scale of the cuts mean that even the areas it is seeking to protect will not be protected fully. An impact assessment — which was so stark that ministers claimed they had to rethink some of the cuts in order to better protect focus areas such as contraception — published alongside the announcement found that there will likely be an end to programs in Malawi where 250,000 young people will lose access to family planning, and 20,000 children risk dropping out of school. “These steep cuts will impact the most marginalized and left behind communities,” said Romilly Greenhill, CEO of Bond, the U.K. network for NGOs, adding: “The U.K. is turning its back on the communities that need support the most.” Last-minute negotiations did see some areas protected from more severe cuts, with the BBC World Service seeing a funding boost, the British Council set to receive an uplift amid its financial struggles, and the Independent Commission for Aid Impact (ICAI) — the aid spending watchdog that had been at risk of being axed — continuing to operate with a 40 percent budget cut. GREEN THREAT Though the move will not require legislation to be confirmed — after Prime Minister Keir Starmer successfully got the move past his MPs last year — MPs inside his party and out have lamented the impact of the cuts, amid the ongoing threat to Labour’s left from a resurgent Green Party under new leader Zack Polanski. Labour MP Becky Cooper, chair of the APPG on global health and security said that her party “is, and always has been, a party of internationalism” but today’s plans would “put Britain and the world at risk.” Sarah Champion, another Labour MP who chairs the House of Commons international development committee said that the announcement confirmed that there “will be no winners from unrelenting U.K. aid cuts, just different degrees of losers,” creating a “desperately bleak” picture for the world’s most vulnerable. “These cuts do not aid our defense, they make the whole world more vulnerable,” she added. Her Labour colleague Gareth Thomas, a former development minister, added: “In an already unsafe world, cutting aid risks alienating key allies and will make improving children’s health and education in Commonwealth countries more difficult.” The announcement may give fresh ammunition to the Greens ahead of May’s local elections, where the party is eyeing up one of its best nights in local government amid a collapse in support for Labour among Britain’s young, progressive, and Muslim voters. Reacting to the news that Britain will cut its aid to developing countries aimed at combatting climate change, Polanski said: “Appalling and just unbelievably short-sighted. Our security here in the U.K. relies on action around the world to tackle the climate crisis.”

World Health Organization officials are preparing for a nuclear catastrophe if the U.S.-Israel war with Iran escalates further. U.N. staff are monitoring the fallout of U.S-Israeli attacks on Iran’s atomic sites and remain “vigilant” for any type of nuclear threat, Hanan Balkhy, WHO regional director for the eastern Mediterranean, told POLITICO. “The worst-case scenario is a nuclear incident, and that’s something that worries us the most,” Balkhy said. “As much as we prepare, there’s nothing that can prevent the harm that will come … the region’s way — and globally if this eventually happens — and the consequences are going to last for decades.” Staff are prepared for a nuclear incident in its “broader sense,” including an attack on a nuclear facility or the use of a weapon, Balkhy said. “We are thinking about it, and we’re just really hoping that it does not happen.” U.S. President Donald Trump has vowed to “eliminate the imminent nuclear threat posed by the Iranian regime,” though he has provided no evidence that Tehran was developing a nuclear weapon. Last June, the U.S. in coordination with Israel targeted nuclear infrastructure throughout Iran. The Atomic Energy Organization of Iran confirmed that attacks took place at its Fordow, Isfahan and Natanz sites. The U.S. and Israel have continued to target nuclear sites since they launched their new offensive on Feb. 28. U.S. President Donald Trump is seen during the his departure the White House en route Hebron, Kentucky on March 11, 2026, in Washington DC. | Celal Gunes/Anadolu via Getty Images Israel and the United Arab Emirates also have nuclear facilities within range of Iran’s missiles, though there are no reports of these being targeted. Israel is itself widely believed to have a significant arsenal of nuclear weapons. To date there have been no reported signs of radioactive contamination anywhere in the region. But if a nuclear incident did expose people to dangerous levels of radiation, it would risk causing significant immediate trauma to their lungs and skin, and heighten the danger of developing cancer and mental health problems, Balkhy explained. The 1986 nuclear accident at the Soviet nuclear plant in Chernobyl, Ukraine officially caused around 30 deaths in the first few months, and later contributed to a surge in thyroid cancers, numbering in the thousands, and to high anxiety among the local population over the following decades. “I think those who read the history of previous incidents, whether intentional or accidental, are very aware of what we’re talking about,” Balkhy said. An estimated 110,000 to 210,000 people died from the U.S. nuclear attacks on the Japanese cities of Hiroshima and Nagasaki in 1945. As the war continues, some senior figures have begun to speculate on the use of nuclear warheads. David Sacks, Trump’s AI adviser, said he worried about “Israel escalating the war by contemplating using a nuclear weapon.” Trump rubbished the suggestion, telling reporters: “Israel wouldn’t do that.” The WHO is refreshing its staff on how to respond in the event of a nuclear incident, including providing advice to officials on the public health risks and what measures people should take to protect themselves.  Smoke rises after airstrikes in Tehran, Iran on March 13, 2026. | Fatemeh Bahrami/Anadolu via Getty Images Balkhy also warned there could be significant health impacts, such as respiratory illness, from the attacks on Iranian oil facilities earlier this month that have covered Tehran in smoke. ATTACKS ON HEALTH SYSTEMS Meanwhile, the WHO has continued to decry attacks on health infrastructure in the region. The WHO has so far recorded 46 attacks on health workers in Iran and Lebanon, with 38 killed, since the war began on Feb. 28. Israel killed 14 health workers in Lebanon in two strikes on March 13, including an attack on the Bourj Qalaouiyeh primary health care center in the south of the country. In a follow-up statement to POLITICO, Balkhy called the attacks “tragic and unacceptable,” adding that health workers must be protected under international law “at all times.” Health workers and United Nations officials have previously accused Israel of systematically destroying Gaza’s health system. Israel has denied that charge, typically stating the attacks are justified on military grounds or, such as in the case of a deadly double-tap strike on Nasser Hospital last year, a “tragic mishap.” By mid-2025, 94 percent of Gaza’s hospitals had been damaged or destroyed, according to the WHO. Kuwait reported on March 17 that two paramedics were injured when shrapnel from an Iranian attack fell on a medical center. A view of tents as Lebanese families who were forced to leave their homes due to Israeli attacks, took shelter in a school building in the Dahieh district of the capital Beirut, Lebanon, on March 15, 2026. | Houssam Shbaro/Anadolu via Getty Images Health ministries in Iran and Lebanon reported 1,444 and 886 civilian deaths, respectively, as of March 17. Lebanon says 107 children have died from the latest bombardment. The United Nations estimates that between 600,000 and 1 million Iranian households have been temporarily displaced, while there are 946,000 self-registered displaced individuals in Lebanon, according to figures provided to POLITICO by the WHO. The Israeli Ministry of Health does not include casualties in its daily updates on the war. As of March 8, the government said 13 people had been killed. The fragile health system in Lebanon, which was already under severe pressure before the latest attacks from Israel, is struggling to deal with the large numbers of displaced. “You’re talking about access to good food, clean water, the disruption of medical care provision, whether it’s childhood immunizations, whether it’s access to their medications, the dialysis patients, the cancer patients, it will have a huge toll on the people of Lebanon,” Balkhy said. An ambulance belonging to the Islamic Health Organisation seen outside Jabal Amel Hospital after an Israeli airstrike in Tyre, Lebanon on March 17, 2026. | Sally Hayden/SOPA Images/LightRocket via Getty Images The conflict is also exacerbating a Palestinian health crisis, with heavy restrictions on the amount of aid entering Gaza, Balkhy said. The WHO has reported critical shortages of medicines and medical supplies in Gaza, despite Israel saying there is enough aid entering the territory to meet humanitarian needs. The Palestinian Ministry of Health, meanwhile, says there are zero stocks of 46 percent of essential medicines. The scale of destruction in Gaza was so overwhelming, Balkhy said, that it would take “billions of dollars” and “decades to re-establish a dignified environment for these people to live in.”

The European Commission has warned that Donald Trump’s latest restrictions on foreign aid are dangerous and threaten global health — while saying the EU can’t fill the funding gap alone. The Trump administration revealed further conditions on foreign aid last week, which seek to restrict NGOs, governments and agencies in receipt of U.S. funding from promoting not only abortion but also “gender ideology” and “discriminatory equity ideology.” The measures come as lower-income countries face catastrophic health impacts after many donors, led by the U.S., dramatically cut funding last year, leaving them with little choice but to accept conditional funds. The policies have appalled health experts who say they are an unprecedented attack on sovereignty and confirm the weaponization of aid under Trump, whose administration is seeking more direct influence over global health programs. Europe has also criticized the expanded policy, stepping up its response compared with more restrained positions to the Trump administration’s other diverging health policies. “Limiting international assistance through restrictive funding conditions undermines joint efforts for human rights, global health, peace and stability. It makes funding more unpredictable and increases the vulnerability of those already most at risk,” European Commission spokesperson Anitta Hipper told POLITICO. “Ultimately, this risks our goal of saving lives,” Hipper said. The EU would assess the implications for the programs it funds and will remain a “credible, reliable, principled and predictable partner,” but Europe “cannot fill the gap left by others,” Hipper added. The new policy is the widest expansion of the Mexico City Policy — which international groups have called the ‘global gag rule’ because of the restrictions it imposes — that the U.S. has ever imposed. U.S. Vice President JD Vance said last week the Trump administration was “expanding this policy to protect life, to combat [diversity, equity and inclusion] and the radical gender ideologies that prey on our children.” He said it would increase the reach of the Mexico City Policy, which has traditionally only applied to abortion advocacy, threefold. It’s the latest policy that underlines the Trump administration’s explicitly strings-attached foreign aid agenda. The U.S. has rolled out a series of bilateral deals with 14 African countries, requiring them to guarantee the U.S. access to pathogen samples and data in exchange for health funding — much of which the U.S. had withdrawn last year through USAID cuts. It has also offered to restore funding to global vaccine program GAVI, but only if the organization stops using a common mercury-based preservative that Trump’s top health officials have linked to autism, without evidence. The latest policy is part of a “much larger project by the Trump administration to advance this radical anti-rights agenda,” Beirne Roose-Snyder, a senior policy fellow at the Council for Global Equality, told reporters this week. Desirée Cormier Smith, a former U.S. diplomat, said she hoped governments in the EU and elsewhere would “push back” and deliver a bracing message to the Trump administration: “We refuse to leave all of our people behind. You’re not going to export your domestic culture wars and the division that plagues the U.S. to our own countries.” The new rules, which come into effect Feb. 26, will also increase pressure on European governments over their own levels of global health funding. Major donors such as France, Germany and the Netherlands have trimmed their own contributions, as part of the global crunch in aid spending. Lisa Goerlitz, head of the Brussels office at global health NGO DSW, said Europe must keep foreign aid spending at levels needed “to allow a credible transition towards domestic resources and new financing mechanisms”. The New York-based Center for Reproductive Rights, meanwhile, said the EU faced a “clear test of its leadership and credibility on equality and human rights.” Claudia Chiappa contributed reporting.

Vice President JD Vance on Friday said the United States will stop funding any organization working on diversity and transgender issues abroad. Vance called the policy, which has been widely expected, “a historic expansion of the Mexico City Policy,” which prevents foreign groups receiving U.S. global health funding from providing or promoting abortion, even if those programs are paid for with other sources of financing. President Donald Trump reinstated the Mexico City Policy last year, following a tradition for Republican presidents that Ronald Reagan started in 1984. Democratic presidents have repeatedly rescinded the policy. “Now we’re expanding this policy to protect life, to combat [diversity, equity and inclusion] and the radical gender ideologies that prey on our children,” Vance told people attending the March for Life in Washington, an annual gathering of anti-abortion activists on the National Mall. The rule covers non-military U.S. foreign assistance, making the Mexico City Policy “about three times as big as it was before, and we’re proud of it because we believe in fighting for life,” Vance said. That means that any organizations receiving U.S. non-military funding will not be able to work on abortion, DEI and issues related to transgender people, even if that work is done with other funding sources. POLITICO reported in October that the Trump administration was developing the policy. The State Department made the rule change Friday afternoon. Vance accused the Biden administration of “exporting abortion and radical gender ideology all around the world.” The Trump administration has used that argument to massively reduce foreign aid since it took office a year ago. Vance said the Trump administration believes that every country in the world has the duty to protect life. “It’s our job to promote families and human flourishing,” he said, adding that the administration “turned off the tap for NGOs whose sole purpose is to dissuade people from having kids.” Chris Smith, a New Jersey Republican who chairs the House Foreign Affairs Africa Subcommittee, called the new aid restrictions “the best and most comprehensive iteration” of the Mexico City Policy since Reagan. Smith, who opposes abortion, was also speaking at the March for Life. But domestic and international groups deplored the expanded policy, noting that it would make women and girls in some parts of the world more vulnerable. “History shows that the Mexico City policy not only diminishes access to essential services for women and girls, but also breaks down networks of organizations working on women’s rights, and silences civil society,” the International Crisis Group, which works to prevent conflicts, said in a statement. “This expansion will amplify those effects and is set to compound the global regression on gender equality that we have seen accelerate in the last year,” the group added. The expanded Mexico City Policy, which international groups have called the ‘global gag rule’ because of the restrictions it imposes, will limit how humanitarian groups and other organizations “can engage in advocacy, information dissemination and education related to reducing maternal mortality, sexual and reproductive health, and reducing stigma and inequalities anywhere in the world, with any funding they receive,” said Defend Public Health, a network of volunteers fighting against the Trump administration’s health policies. “This would effectively coerce them into denying that transgender, nonbinary, and intersex people exist,” the group said. Alice Miranda Ollstein contributed to this report.

The German government rejected claims by U.S. Health Secretary Robert F. Kennedy Jr. that Berlin prosecuted doctors and patients for refusing Covid-19 vaccinations or mask mandates. “The statements made by the U.S. Secretary of Health are completely unfounded, factually incorrect, and must be rejected,” German Health Minister Nina Warken said in a statement late Saturday. “I can happily explain this to him personally,” she said. “At no time during the coronavirus pandemic was there any obligation for doctors to carry out vaccines against Covid-19,” Warken added. “Anyone who did not wish to offer vaccines for medical, ethical or personal reasons were not criminally liable and did not have to fear penalties,” she said. Warken added that “criminal prosecution took place only in cases of fraud and forgery of documents, such as the issuing of false vaccine certificates” or exemption certificates for masks.  “Doctors [in Germany] decide independently and autonomously on the treatment of patients,” the minister stressed, adding that “patients are also free to decide which treatment they wish to receive.” Kennedy said in a video post on Saturday that he had written to Warken after receiving reports that Germany was restricting “people’s abilities to act on their own convictions” in medical decisions. He claimed that “more than a thousand German physicians and thousands of their patients” faced prosecution for issuing exemptions from mask-wearing or Covid-19 vaccination requirements during the pandemic. Kennedy did not provide specific examples or identify the reports he cited, but he said Germany was “targeting physicians who put their patients first” and was “punishing citizens for making their own medical choices.” He accused Berlin of undermining the doctor–patient relationship and replacing it with “a dangerous system that makes physicians enforcers of state policies.” Former German Health Minister Karl Lauterbach also pushed back on the claims, telling Kennedy on X to “take care of health problems in his own country.”

The billionaire Microsoft founder, Bill Gates, has become the world’s leading global health philanthropist, but his overture to the late, convicted sex offender Jeffrey Epstein continues to haunt him, most recently with the release of photos Friday featuring him in the American financier’s entourage. Gates appears in two images Democrats on the House Oversight and Government Reform Committee released, the first batch in what’s expected to be 95,000 photos. The committee is reviewing documents from the Epstein estate as part of its ongoing investigation. Epstein does not appear in the two pictures Gates is in. In one, Gates is standing next to Andrew Mountbatten-Windsor, formerly Prince Andrew. In 2019, Mountbatten-Windsor was accused in a civil lawsuit of sexually assaulting Virginia Giuffre, one of Epstein’s accusers, but he denied the allegations. Mountbatten-Windsor has faced backlash for his friendship with Epstein, but has not been charged with a crime in either the U.K. or the U.S. A second picture shows a younger Gates next to a man who appears to be one of Epstein’s longtime pilots. Representatives for Gates and his global health philanthropy, the Gates Foundation, did not immediately respond to requests for comment. Gates has said he had several dinners with Epstein, who promised to get his wealthy connections to donate money to global health. When that didn’t happen, Gates cut off the dinners, Gates told PBS NewsHour in 2021. “Those meetings were a mistake,” Gates said. Gates’ former wife, Melinda French Gates, has said she didn’t like her then-husband meeting with Epstein and suggested those meetings contributed to the couple’s 2021 divorce. French Gates told CBS in a 2022 interview she met Epstein once, “because I wanted to see who this man was. I regretted it from the second I stepped in the door. He was abhorrent, he was evil personified. I had nightmares about it afterwards.” When Bill Gates was asked in a January 2023 interview with ABC Australia whether French Gates had warned him against ties with Epstein, because “Epstein had a way of sexually compromising people,” as the anchor put it, Bill Gates replied: “No! I had dinner with him, and that’s all.” An interview with Gates POLITICO published Friday was conducted before the release of the photos.

The World Health Organization has recommended the use of novel weight-loss drugs to curb soaring obesity rates, and urged pharma companies to lower their prices and expand production so that lower-income countries can also benefit. The WHO’s new treatment guideline includes a conditional recommendation to use the so-called GLP-1s — such as Wegovy, Ozempic and Mounjaro — as part of a wider approach that includes healthy diet, exercise and support from doctors. The WHO described its recommendation as “conditional” due to limited data on the long-term efficacy and safety of GLP-1s. The recommendation excludes pregnant women. While GLP-1s are a now well-established treatment in high-income countries, the WHO warns they could reach fewer than 10 percent of people who could benefit by 2030. Among the countries with the highest rates of obesity are those in the Middle East, Latin America and Pacific islands. Meanwhile, Wegovy was only available in around 15 countries as of the start of this year. The WHO wants pharma companies to consider tiered pricing (lower prices in lower-income countries) and voluntary licensing of patents and technology to allow other producers around the word to manufacture GLP-1s, to help expand access to these drugs. Jeremy Farrar, an assistant director general at the WHO, told POLITICO the guidelines would also give an “amber and green light” to generic drugmakers to produce cheaper versions of GLP-1s when the patents expire. Francesca Celletti, a senior adviser on obesity at the WHO, told POLITICO “decisive action” was needed to expand access to GLP-1s, citing the example of antiretroviral HIV drugs earlier this century. “We all thought it was impossible … and then the price went down,” she said.  Key patents on semaglutide, the ingredient in Novo Nordisk’s diabetes and weight-loss drugs Ozempic and Wegovy, will lift in some countries next year, including India, Brazil and China. Indian generics giant Dr. Reddy’s plans to launch a generic semaglutide-based weight-loss drug in 87 countries in 2026, its CEO Erez Israeli said earlier this year, reported Reuters. “U.S. and Europe will open later … (and) all the other Western markets will be open between 2029 to 2033,” Israeli told reporters after the release of quarterly earnings in July. Prices should fall once generics are on the market, but that isn’t the only barrier. Injectable drugs, for example, need cold chain storage. And health systems need to be equipped to roll out the drug once it’s affordable, Celletti said. 

Pediatric respiratory diseases are among the most common and serious health challenges we face worldwide. From examples such as respiratory syncytial virus (RSV) to pertussis (also known as whooping cough), these infections can cause significant illness, hospitalizations, and with some, possible long-term consequences.[1],[2] Worldwide, RSV causes approximately 3.6 million hospitalizations and 100,000 deaths each year in children under five years of age.[3] Yet, many of these infections may be prevented, if we continue to prioritize and strengthen immunization. Immunization is not just a scientific achievement; it’s a public health imperative. And in this new era, Sanofi is at the forefront, driving innovation and access to pediatric immunization, especially when it comes to respiratory disease prevention. Our commitment is global, our ambition bold: to help protect people everywhere against preventable illnesses, with the confidence that every child, every parent, every person, and every healthcare professional deserves. > Immunization is not just a scientific achievement; it’s a public health > imperative. RSV, a leading cause of infant hospitalizations globally, exemplifies both the challenge and the opportunity.[4],[5],[6],[7] With an estimated 12.9 million lower respiratory infections and 2.2 million hospitalizations annually among infants under one year of age,3 the burden is immense. For decades, RSV lacked preventive options for the broad infant population. Some countries in Europe are a good illustration of what is possible when prevention is prioritized. For example, in Galicia, Spain, implementation of a universal program offered to the broad infant population led to notable reductions in RSV-related hospitalization compared with previous seasons.[8] The lesson is clear: when prevention is prioritized like it matters, delivered equitably and integrated into routine care, the impact is quickly seen. This principle applies to other childhood respiratory diseases. Hexavalent combination vaccinations have helped to revolutionize pediatric immunization by combining protection against six diseases into one vaccine. One of these is pertussis, which is especially dangerous for children who haven’t received all their vaccinations yet, and have a four-fold higher risk of contracting whooping cough.[9]  For younger infants pertussis is high risk, with over 40 percent of infants under six months of age requiring hospitalization.[10] These data demonstrate how delayed or missed vaccine doses can leave children vulnerable. By combining vaccines into a single shot, immunization uptake can be improved, increasing acceptance with efficient and equitable delivery and helping reduce disease burden at scale.[11],[12] > Some countries in Europe are a good illustration of what is possible when > prevention is prioritized. For example, in Galicia, Spain, implementation of a > universal program offered to the broad infant population led to notable > reductions in RSV-related hospitalization compared with previous seasons. Good uptake is crucial for protecting children. Where programs are fragmented, under-resourced or underfunded, equity gaps worsen along familiar lines – income, access and information. The recent resurgence of some preventable diseases is not just a warning; it’s a call to action.[13],[14],[15] Sustaining protection against respiratory diseases in children, increasing vaccination coverage rates, and embracing innovation to help protect against more diseases must be a collective priority.[11],[12] We must not let misinformation or complacency erode public trust in immunization. The evidence is clear: prevention works. Today, we have a unique opportunity to showcase that impact and redefine the future of respiratory health in children. > We must not let misinformation or complacency erode public trust in > immunization. The evidence is clear: prevention works. The science is sound. The approach for protecting infants against respiratory infections is clear. Our children deserve nothing less. -------------------------------------------------------------------------------- [1] Glaser EL, et al. Impact of Respiratory Syncytial Virus on Child, Caregiver, and Society. Journal of Infectious Diseases. 2022;226(Supplement_2):S236-S241 [2] Kardos P, et al. Understanding the impact of adult pertussis and its complications. Hum Vaccin Immunother. 2024. [3] Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis. Lancet 2022;399:2047-2064. [4] Leader S, Kohlhase K. Respiratory syncytial virus-coded pediatric hospitalizations, 1997 to 1999. The Pediatric infectious disease journal. 2002;21(7):629-32. [5] McLaurin KK, Farr AM, Wade SW, Diakun DR, Stewart DL. Respiratory syncytial virus hospitalization outcomes and costs of full-term and preterm infants. Journal of Perinatology: official journal of the California Perinatal Association. 2016;36(11):990-6. [6] Rha B, et al. Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016. Pediatrics. 2020;146:e20193611. [7] Arriola CS, et al. Estimated Burden of Community-Onset Respiratory Syncytial Virus-Associated Hospitalizations Among Children Aged <2 Years in the United States, 2014-15. J Pediatric Infect Dis Soc. 2020;9:587-595. [8] Ares-Gómez S, et al. NIRSE-GAL Study Group. Effectiveness and impact of universal prophylaxis with nirsevimab in infants against hospitalisation for respiratory syncytial virus in Galicia, Spain: initial results of a population-based longitudinal study. Lancet Infectious Diseases. 2024; 24: 817-828. [9] Centers for Disease Control and Prevention. 2019 Final Pertussis Surveillance Report. Accessed 4 March 2025 [10] Glanz, J. M., et al. (2013) Association between undervaccination with diphtheria, tetanus toxoids, and acellular pertussis (DTaP) vaccine and risk of pertussis infection in children 3 to 36 months of age. JAMA Pediatr. doi: 10.1001/jamapediatrics.2013.2353 [11] Fatima M, Hong KJ. Innovations, Challenges, and Future Prospects for Combination Vaccines Against Human Infections. Vaccines (Basel). 2025 Mar 21;13(4):335. doi: 10.3390/vaccines13040335. PMID: 40333234; PMCID: PMC12031483. [12] Maman K, Zöllner Y, Greco D, Duru G, Sendyona S, Remy V. The value of childhood combination vaccines: From beliefs to evidence. Hum Vaccin Immunother. 2015;11(9):2132-41. doi: 10.1080/21645515.2015.1044180. PMID: 26075806; PMCID: PMC4635899. [13] Liu J, Lu G, Qiao J. Global resurgence of pertussis in infants BMJ 2025; 391 :r2169 doi:10.1136/bmj.r2169 [14] Jenco M. AAP, CHA call for emergency declaration to address surge of pediatric illnesses. AAP News. 2022 [15] Wang, S., Zhang, S., & Liu, J. (2025). Resurgence of pertussis: Epidemiological trends, contributing factors, challenges, and recommendations for vaccination and surveillance. Human Vaccines & Immunotherapeutics, 21(1). https://doi.org/10.1080/21645515.2025.2513729 MAT-GLB-2506084