The UK has historically been a global leader in life sciences innovation, but
recent statistics paint a worrying picture for medicines access. The right
policy can start to reverse this.
We are living in a time where the intersection between breakthrough science,
technology and data insights has the potential to transform treatment options
for some of the toughest health conditions faced by patients in the UK.
The UK has long played a central role in driving innovation when it comes to
healthcare, and at Johnson & Johnson (J&J) we were pleased to see some positive
signs from the Government at the end of 2025, illustrating an intent to reverse
a decade of decline of investment in how the UK values innovative treatments.
It was a positive first step, but now the real work begins to enable us to
deliver the best possible outcomes for UK patients. To achieve this, our focus
must be on ensuring our health system is set up to match the pace and gain the
benefits of innovation that science provides. We need a supportive medicines
environment that fully fosters growth, because even the most pioneering drugs
and therapies are only valuable if they can be accessed by patients when they
need them most.
> even the most pioneering drugs and therapies are only valuable if they can be
> accessed by patients when they need them most.
At J&J, we are proud to have been part of the UK’s health innovation story for
more than a century. We believe that turning ambition into delivery requires a
clearer focus on the foundations that enable innovation to reach patients. We
have had a substantial and long-term economic presence, with our expertise
serving as the grounds for successful partnerships with patients, healthcare
providers, clinical researchers and the NHS.
Recent national developments are a step in the right direction
The UK Government’s recent announcements on the life sciences industry are an
important move to help address concerns around medicines access, innovation and
the UK’s international standing. This includes a welcome planned increase to the
baseline cost-effectiveness threshold (the first change to be made since its
introduction in the early 2000s).
While it is crucial to get this implemented properly, this seems like a step in
the right direction — providing a starting point towards meaningful policy
reform, industry partnership and progress for patients.
The true impact of stifling medicine innovation in the UK compared with our
peers
These positive developments come at a critical time, but they do not fix
everything.
Over the past decade, spending on branded medicines has fallen in real terms,
even as the NHS budget has grown by a third.[i] Years of cost-containment have
left the UK health system ill-prepared for the health challenges of today, with
short-term savings creating long-term consequences. Right now, access to
innovative medicines in the UK lags behind almost every major European
country[ii]; the UK ranks 16th and 18th among 19 comparable countries for
preventable and treatable causes of mortality.[iii]These are conditions for
which effective medicines already exist.
Even when new medicines are approved, access is often restricted. One year after
launch, usage of innovative treatments in England is just over half the average
of comparator countries such as France, Germany and Spain.[iv] The effect is
that people living with cancer, autoimmune conditions and rare diseases wait
longer to access therapies that are already transforming lives elsewhere in
Europe.
And even at its new level, the UK’s Voluntary Scheme for Branded Medicines
Pricing, Access and Growth (VPAG) clawback rate remains higher than in
comparable countries.[v] J&J is committed to working together to develop a new
pricing and access framework that is stable, predictable and internationally
competitive — enabling the UK to regain its position as a leading destination
for life sciences.
Seeing the value of health and medicines investment as a catalyst for prosperity
and growth
Timely access to the right treatment achieves two things; it keeps people
healthy and prevents disease worsening so they can participate in society and a
thriving economy. New research from the WifOR Institute, funded by J&J, shows
that countries that allocate more resources to health — especially when combined
with a skilled workforce and strong infrastructure — consistently achieve better
outcomes.[vi]
> Timely access to the right treatment achieves two things; it keeps people
> healthy and prevents disease worsening so they can participate in society and
> a thriving economy.
The UK Government’s recent recognition of the need for long-term change, setting
out plans to increase investment in new medicines from 0.3 percent of GDP to 0.6
percent over the next 10 years is positive. It signals a move towards seeing
health as one of our smartest long-term investments, underpinning the UK’s
international competitiveness by beginning to bring us nearer to the levels in
other major European countries.
This mindset shift is critical to getting medicines to patients, and the life
sciences ecosystem, including the pharmaceutical sector as a cornerstone, plays
a pivotal role. It operates as a virtuous cycle — driven by the generation,
production, investment in, access to and uptake of innovation. Exciting
scientific developments and evolving treatment pathways mean that we have an
opportunity to review the structures around medicines reimbursement to ensure
they remain sustainable, competitive and responsive. At J&J, we have the
knowledge and heritage to work hand-in-hand with the Government and all partners
to achieve this.
Together, we can realise the potential of medicine innovation in the UK
Patients have the right to expect that science and innovation will reach them
when they need it. Innovative treatments can be transformative for patients,
meaning an improved quality of life or more precious time with loved ones.
We fully support the Government’s ambitions for life sciences and the health of
the nation. Now is the moment to deliver meaningful change — the NHS, Government
and all system partners, including J&J, must look at what valuing innovation
actually means when it comes to modernising the frameworks and mechanisms that
support access and uptake. Practical ways to do this include:
* Establishing a new pricing and access framework that is stable, predictable
and internationally competitive.
* Evolving medicines appraisal methods and processes, to deliver on the
commitments of the UK-US Economic Prosperity Deal.
* Adapting thresholds and value frameworks to ensure they are fit for the
future — in the context of wider system pressures, including inflation, and
the evolution of medical innovation requiring new approaches to assessment
and access.
> the NHS, Government and all system partners, including J&J, must look at what
> valuing innovation actually means when it comes to modernising the frameworks
> and mechanisms that support access and uptake.
By truly recognising the value of health as an investment, rather than as a
cost, we can return the UK to a more competitive position. The direction of
travel is positive. At J&J, we stand ready to work in partnership to help ensure
the UK is once again the best place in the world to research, develop and access
medicines.
Follow Johnson & Johnson Innovative Medicine UK on LinkedIn for updates on our
business, our people and our community.
CP-562703 | January 2026
--------------------------------------------------------------------------------
[i] House of Commons Library (2026). ‘NHS Funding and Expenditure’ Research
Briefing. Available at:
https://commonslibrary.parliament.uk/research-briefings/sn00724/ (Accessed
January 2026).
[ii] IQVIA & EFPIA (2025). EFPIA Patients W.A.I.T Indicator 2024 Survey.
Available at:
https://efpia.eu/media/oeganukm/efpia-patients-wait-indicator-2024-final-110425.pdf.
(Accessed January 2026)
[iii] The Kings Fund (2022). ‘How does the NHS compare to the health care
systems of other countries?’ Available at:
https://www.kingsfund.org.uk/insight-and-analysis/reports/nhs-compare-health-care-systems-other-countries
(Accessed January 2026)
[iv] Office for Life Sciences (2024). Life sciences competitiveness indicators
2024: summary. Available at:
https://www.gov.uk/government/publications/life-sciences-sector-data-2024/life-sciences-competitiveness-indicators-2024-summary
(Accessed January 2026).
[v] ABPI. VPAG payment rate for newer medicines will be 14.5% in 2026. December
2025. Available at:
https://www.abpi.org.uk/media/news/2025/december/vpag-payment-rate-for-newer-medicines-will-be-145-in-2026/.
(Accessed January 2026).
[vi] WifOR Institute (2025). Healthy Returns: A Catalyst for Economic Growth and
Resilience. Available at:
https://www.wifor.com/en/download/healthy-returns-a-catalyst-for-economic-growth-and-resilience/?wpdmdl=360794&refresh=6942abe7a7f511765977063.
(Accessed January 2026).
Tag - healthcare
LONDON — It’s a far cry from the ice age of U.K.-China relations that
characterized Rishi Sunak’s leadership — and it’s not exactly David Cameron’s
“golden era,” either.
As U.K. Prime Minister Keir Starmer embarks on his Chinese charm offensive
against a turbulent economic backdrop, he has opted for a softly-softly approach
in a bid to warm up one of Britain’s most important trading partners — a marked
departure from his Tory predecessors.
With the specter of U.S. President Donald Trump looming over the visit — not to
mention national security concerns back home — Starmer’s cautious optimism is
hardly surprising.
Despite reservations from China skeptics, Starmer’s trip — the first such visit
by a British prime minister since 2018 — was peppered with warm words and a
smattering of deals, some more consequential than others.
Britain’s haul from the trip may be modest, but it’s just the beginning,
Business and Trade Secretary Peter Kyle — who joined Starmer on the trip — told
a traveling pack of reporters in Beijing.
“This visit is a springboard,” the minister said. “This is not the last moment,
it is a springboard into a future with far more action to come.”
STEP-BY-STEP
On the ground in Beijing, British officials gave the impression that the prime
minister was focused on getting as many uncontroversial wins over the line as
possible, in a bid to thaw relations with China.
That’s not to say Starmer and his team don’t have a few tangible wins to write
home about. Headline announcements include a commitment from China to allow
visa-free travel for British tourists and business travelers, enabling visits of
up to 30 days without the need for documents.
The provisions are similar to those extended to 50 other countries including
France, Germany, Italy, Australia and Japan. The timings of the visa change have
not yet been set out publicly, but one official — who, like others cited in this
piece, was granted anonymity to speak freely — said they were aiming to get it
nailed down in coming months.
“From a business standpoint, it will reduce a lot of friction,” said a British
business representative, adding it will make it easier for U.K. firms to explore
opportunities and form partnerships. “China is very complicated. You have to be
on the ground to really assess opportunities,” they said, adding visa-free
travel “will make things a lot easier.”
The commitment to visa-free travel forms part of a wider services package aimed
at driving collaboration for businesses in healthcare, financial and
professional services, legal services, education and skills — areas where
British firms often face regulatory or administrative hurdles.
The countries have also agreed to conduct a “feasibility study” to explore
whether to enter negotiations towards a bilateral services agreement. If it goes
ahead, this would establish clear and legally binding rules for U.K. firms doing
business in China. Once again, the timeframe is vague.
David Taylor, head of policy at the Asia House think tank in London, said “Xi’s
language has been warmer and more expansive, signaling interest in stabilizing
the relationship, but the substance on offer so far remains tightly defined.”
“Beyond the immediate announcements, progress — particularly on services and
professional access — will be harder and slower if it happens at all,” he added.
WHISKY TARIFF RELIEF
Another victory talked up by the British government is a plan for China to slash
Scotch whisky tariffs by half, from 10 percent to 5 percent.
However, some may question the scale of the commitment, which effectively
restores the rate that was in place one year ago, ahead of a doubling of the
rate for whisky and brandy in February 2025.
The two sides have not yet set out a timeframe for the reduction of tariffs.
Speaking to POLITICO ahead of Starmer’s trip, a senior business representative
said the whisky and brandy issue had become “China leverage” in talks leading up
to the visit. However, they argued that even a removal of the tariff was “not
going to solve the main issue for British whisky companies in China and
everywhere, which is that people aren’t buying and drinking whisky.”
CHINA INVESTMENT WIN
Meanwhile, China can boast a significant win in the form of a $15 billion
investment in medicines manufacturing and research and development from British
pharmaceutical giant AstraZeneca.
ING Bank’s global healthcare lead Stephen Farelly said that increasing
investment into China “makes good business sense,” given the country is “now
becoming a force in biopharma.” However, it “does shine a light on the isolation
of Europe and the U.K. more generally, where there is a structural decline in
investment and R&D.”
AstraZeneca recently paused a £200 million investment at a Cambridge research
site in September last year, which was due to create 1,000 jobs.
Britain recently increased the amount the NHS pays for branded, pharmaceutical
drugs, following heavy industry lobbying and following trade negotiations with
the Trump administration — all in the hopes of attracting new investment into
the struggling sector.
Shadow Trade Secretary Andrew Griffith was blunt in his assessment.
“AstraZeneca’s a great British company but under this government it’s investing
everywhere in the world other than its U.K. home. When we are losing investment
to communist China, alarm bells should be ringing in No 10 Downing Street.”
Conspicuously absent from Starmer’s haul was any mention of net zero
infrastructure imports, like solar panels, a reflection of rising concerns about
China’s grip on Britain’s critical infrastructure.
XI RETURNS
So what next? As Starmer prepares to fly back home, attention has already turned
to his next encounter with the Chinese leader.
On Thursday, Britain opened the door to an inward visit by Xi Jinping, with
Downing Street repeatedly declining to rule out the prospect of welcoming him in
future.
Asked about the prospect of an inward visit — which would be the first for 11
years — Starmer’s official spokesperson told reporters: “I think the prime
minister has been clear that a reset relationship with China, that it’s no
longer in an ice age, is beneficial to British people and British business.”
As Starmer’s trip draws to a close, one thing is certain: there is more to come.
“This isn’t a question of a one-and-done summit with China,” Starmer’s
spokesperson added. “It is a resetting of a relationship that has been on ice
for eight years.”
The U.K. and China have announced a new services partnership to support British
businesses operating in China, including through visa-free travel for short
stays.
The partnership will see Beijing relax its visa rules for British citizens,
adding the U.K. to its visa-free list of countries. This will enable visits of
up to 30 days for business and tourism without the need for a visa. The timings
of the visa change have not yet been set out.
The partnership focuses on better collaboration for businesses in healthcare,
financial and professional services, legal services, education and skills —
areas where British firms often face regulatory or administrative hurdles.
Britain and China have also agreed to conduct a “feasibility study” to explore
whether to enter negotiations towards a bilateral services agreement. If it
proceeds, this would establish clear and legally binding rules for U.K. firms
doing business in China.
Prime Minister Keir Starmer said: “As one of the world’s economic powerhouses,
businesses have been crying out for ways to grow their footprints in China.
“We’ll make it easier for them to do so – including via relaxed visa rules for
short-term travel — supporting them to expand abroad, all while boosting growth
and jobs at home.”
The U.K. and China have also signed pacts covering co-operation on conformity
assessments for exports from the U.K. to China, food safety, animal, and plant
quarantine health and the work the UK-China Joint Economic and Trade Commission.
The two sides aren’t planning to publish the full texts of the pacts.
BEIJING — U.K. Prime Minister Keir Starmer has hailed “really good progress” on
Chinese whisky tariffs and visa-free travel after a lengthy meeting with Chinese
President Xi Jinping.
Starmer dubbed the one hour and 20 minute sit-down with Xi as “a very good
productive session with real, concrete outcomes, [which was] a real
strengthening of the relationship.”
Speaking to reporters after the meeting, he said: “We made some really good
progress on tariffs for whisky, on visa free travel to China and on information
exchange.”
The news will be welcomed by Scotch whisky exporters, who have been squeezed by
U.S. President Donald Trump’s 10 percent baseline tariffs on imported U.K.
goods.
Currently, Scotch whisky exports face 10 percent duties in China, after the
country doubled its import tariffs on brandy and whisky in February 2025,
removing its provisional 5 percent rate.
Exports to China fell by 31 percent last year, sliding from China’s
fifth-largest export market to its tenth.
“We’ve agreed that on tariffs for whisky, we’re looking at how they’re to be
reduced, what the timeframe is,” said Starmer.
The two sides also made progress on visa-free travel to China for short stays —
which would allow British citizens to visit for tourism, business conferences,
family visits, and short exchange activities without requiring a visa.
Britain is currently not among the European countries granted visa-free access
to China, a list that includes France, Germany, Italy, Spain, and Switzerland.
Starmer said the two sides are now looking at “how far, how much, and when that
can start.”
China issued its own readout via state news agency Xinhua, where it discussed
expanded cooperation in “education, healthcare, finance, and services, and
conduct joint research and industrial transformation in fields such as
artificial intelligence, bioscience, new energy, and low-carbon technologies to
achieve common development and prosperity.”
The Chinese statement said both sides should “strengthen people-to-people
exchanges and further facilitate personnel exchanges,” adding that China “is
willing to actively consider implementing unilateral visa-free entry for the
U.K.”
Starmer and Chinese Premier Li Qiang are due to sign memorandums of
understanding covering cooperation in a number of areas at a signing ceremony on
Thursday morning U.K. time.
Starmer and Li will also sign a border security pact to enlist Beijing’s help in
choking off the supply of small boat engines and equipment used by criminal
gangs to facilitate Channel crossings
POLITICO first reported earlier this month that the U.K. was pushing to secure
visa-free travel and lower whisky tariffs.
This developing story is being updated.
LONDON — Keir Starmer is off to China to try to lock in some economic wins he
can shout about back home. But some of the trickiest trade issues are already
being placed firmly in the “too difficult” box.
The U.K.’s trade ministry quietly dispatched several delegations to Beijing over
the fall to hash out deals with the Chinese commerce ministry and lay the
groundwork for the British prime minister’s visit, which gets going in earnest
Wednesday.
But the visit comes as Britain faces growing pressure from its Western allies to
combat Chinese industrial overproduction — and just weeks after Starmer handed
his trade chief new powers to move faster in imposing tariffs on cheap,
subsidized imports from countries like China.
For now, then, the aim is to secure progress in areas that are seen as less
sensitive.
Starmer’s delegation of CEOs and chairs will split their time between Beijing
and Shanghai, with executives representing City giants and high-profile British
brands including HSBC, Standard Chartered, Schroders, and the London Stock
Exchange Group, alongside AstraZeneca, Jaguar Land Rover, Octopus Energy, and
Brompton filling out the cast list. Starmer will be flanked on his visit by
Trade Secretary Peter Kyle and City Minister Lucy Rigby.
Despite the weighty delegation, ministers insist the approach is deliberately
narrow.
“We have a very clear-eyed approach when it comes to China,” Security Minister
Dan Jarvis said Monday. “Where it is in our national interest to cooperate and
work closely with [China], then we will do so. But when it’s our national
security interest to safeguard against the threats that [they] pose, we will
absolutely do that.”
Starmer’s wishlist will be carefully calibrated not to rock the boat. Drumming
up Chinese cash for heavy energy infrastructure, including sensitive wind
turbine technology, is off the table.
Instead, the U.K. has been pushing for lower whisky tariffs, improved market
access for services firms, recognition of professional qualifications, banking
and insurance licences for British companies operating in China, easier
cross-border investment, and visa-free travel for short stays.
With China fiercely protective of its domestic market, some of those asks will
be easier said than done. Here’s POLITICO’s pro guide to where it could get
bumpy.
CHAMPIONING THE CITY OF LONDON
Britain’s share of China’s services market was a modest 2.7 percent in 2024 —
and U.K. firms are itching for more work in the country.
British officials have been pushing for recognition of professional
qualifications for accountants, designers and architects — which would allow
professionals to practice in China without re-licensing locally — and visa-free
travel for short stays.
Vocational accreditation is a “long-standing issue” in the bilateral
relationship, with “little movement” so far on persuading Beijing to recognize
U.K. professional credentials as equivalent to its own, according to a senior
industry representative familiar with the talks, who, like others in this
report, was granted anonymity to speak freely.
But while the U.K.’s allies in the European Union and the U.S. have imposed
tariffs on Chinese EVs, the U.K. has resisted pressure to do so. | Jessica
Lee/EPA
Britain is one of the few developed countries still missing from China’s
visa-free list, which now includes France, Germany, Italy, Spain, the
Netherlands, Switzerland, Australia, New Zealand, Japan, Saudi Arabia, Russia
and Sweden.
Starmer is hoping to mirror a deal struck by Canadian PM Mark Carney, whose own
China visit unlocked visa-free travel for Canadians.
The hope is that easier business travel will reduce friction and make it easier
for people to travel and explore opportunities on the ground — it would allow
visa-free travel for British citizens, giving them the ability to travel for
tourism, attend business conferences, visit friends and family, and participate
in short exchange activities.
SMOOTHING FINANCIAL FLOWS
The Financial Conduct Authority’s Chair Ashley Alder is also flying out to
Beijing, hoping to secure closer alignment between the two countries’ capital
markets. He’ll represent Britain’s financial watchdog at the inaugural U.K-China
Financial Working Group in Beijing — and bang the drum for better market
connectivity between the U.K. and China.
Expect emphasis on the cross-border investments mechanism known as the
Shanghai-London and Shenzhen-London Stock Connect, plus data sovereignty issues
associated with Chinese companies jointly listing on the London Stock Exchange,
two figures familiar with the planning said.
The Stock Connect opened up both markets to investors in 2019 which, according
to FCA Chair Ashley Alder, led to listings worth almost $6 billion.
“Technical obstacles have so far prevented us from realizing Stock Connect’s
full potential,” Alder said in a speech last year. Alder pointed to a memorandum
of understanding being drawn up between the FCA and China’s National Financial
Regulatory Administration, which he said is “critical” to allow information to
be shared quickly and for firms to be supervised across borders. But that raises
its own concerns about Chinese use of data.
“The goods wins are easier,” said a senior British business representative
briefed on the talks. “Some of the service ones are more difficult.”
TAPPING INTO CHINA’S BIOTECH BOOM
Pharma executives, including AstraZeneca’s CEO Pascal Soriot, are among those
heading to China, as Britain tries to burnish its credentials as a global life
sciences hub — and attract foreign direct investment.
China, once known mainly for generics — cheaper versions of branded medicine
that deliver the same treatment — has rapidly emerged as a pharma powerhouse.
According to ING Bank’s global healthcare lead, Stephen Farrelly, the country
has “effectively replaced Europe” as a center of innovation.
ING data shows China’s share of global innovative drug approvals jumped from
just 4 percent in 2014 to 27 percent in 2024.
Pharma executives, including AstraZeneca’s CEO Pascal Soriot, are among those
heading to China, as Britain tries to burnish its credentials as a global life
sciences hub — and attract foreign direct investment. | John G. Mabanglo/EPA
Several blockbuster drug patents are set to expire in the coming years, opening
the door for cheaper generic competitors. To refill thinning pipelines,
drugmakers are increasingly turning to biotech companies. British pharma giant
GSK signed a licensing deal with Chinese biotech firm Hengrui Pharma last July.
“Because of the increasing relevance of China, the big pharma industry and the
U.K. by definition is now looking to China as a source of those new innovative
therapies,” Farrelly said.
There are already signs of progress. Science Minister Patrick Vallance said late
last year that the U.K. and China are ready to work together in
“uncontroversial” areas, including health, after talks with his Chinese
counterpart. AstraZeneca, the University of Cambridge and Beijing municipal
parties have already signed a partnership to share expertise.
And earlier this year, the U.K. announced plans to become a “global first choice
for clinical trials.”
“The U.K. can really help China with the trust gap” when it comes to getting
drugs onto the market, said Quin Wills, CEO of Ochre, a biotech company
operating in New York, Oxford and Taiwan. “The U.K. could become a global gold
stamp for China. We could be like a regulatory bridgehead where [healthcare
regulator] MHRA, now separate from the EU since Brexit, can do its own thing and
can maybe offer a 150-day streamlined clinical approval process for China as
part of a broader agreement.”
SLASHING WHISKY TARIFFS
The U.K. has also been pushing for lowered tariffs on whisky alongside wider
agri-food market access, according to two of the industry figures familiar with
the planning cited earlier.
Talks at the end of 2024 between then-Trade Secretary Jonathan Reynolds and his
Chinese counterpart ended Covid-era restrictions on exports, reopening pork
market access.
But in February 2025 China doubled its import tariffs on brandy and whisky,
removing its provisional 5 percent tariff and applying the 10 percent
most-favored-nation rate.
“The whisky and brandy issue became China leverage,” said the senior British
business representative briefed on the talks. “I think that they’re probably
going to get rid of the tariff.”
It’s not yet clear how China would lower whisky tariffs without breaching World
Trade Organization rules, which say it would have to lower its tariffs to all
other countries too.
INDUSTRIAL TENSIONS
The trip comes as the U.K. faces growing international pressure to take a
tougher line on Chinese industrial overproduction, particularly of steel and
electric cars.
But in February 2025 China doubled its import tariffs on brandy and whisky,
removing its provisional 5 percent tariff and applying the 10 percent
most-favored-nation rate. | Yonhap/EPA
But while the U.K.’s allies in the European Union and the U.S. have imposed
tariffs on Chinese EVs, the U.K. has resisted pressure to do so.
There’s a deal “in the works” between Chinese EV maker and Jaguar Land Rover,
said the senior British business representative briefed on the talks quoted
higher, where the two are “looking for a big investment announcement. But
nothing has been agreed.” The deal would see the Chinese EV maker use JLR’s
factory in the U.K. to build cars in Britain, the FT reported last week.
“Chinese companies are increasingly focused on localising their operations,”
said another business representative familiar with the talks, noting Chinese EV
makers are “realising that just flaunting their products overseas won’t be a
sustainable long term model.”
It’s unlikely Starmer will land a deal on heavy energy infrastructure, including
wind turbine technology, that could leave Britain vulnerable to China. The U.K.
has still not decided whether to let Ming Yang, a Chinese firm, invest £1.5
billion in a wind farm off the coast of Scotland.
The German government rejected claims by U.S. Health Secretary Robert F. Kennedy
Jr. that Berlin prosecuted doctors and patients for refusing Covid-19
vaccinations or mask mandates.
“The statements made by the U.S. Secretary of Health are completely unfounded,
factually incorrect, and must be rejected,” German Health Minister Nina Warken
said in a statement late Saturday.
“I can happily explain this to him personally,” she said. “At no time during the
coronavirus pandemic was there any obligation for doctors to carry out vaccines
against Covid-19,” Warken added.
“Anyone who did not wish to offer vaccines for medical, ethical or personal
reasons were not criminally liable and did not have to fear penalties,” she
said.
Warken added that “criminal prosecution took place only in cases of fraud and
forgery of documents, such as the issuing of false vaccine certificates” or
exemption certificates for masks.
“Doctors [in Germany] decide independently and autonomously on the treatment of
patients,” the minister stressed, adding that “patients are also free to decide
which treatment they wish to receive.”
Kennedy said in a video post on Saturday that he had written to Warken after
receiving reports that Germany was restricting “people’s abilities to act on
their own convictions” in medical decisions.
He claimed that “more than a thousand German physicians and thousands of their
patients” faced prosecution for issuing exemptions from mask-wearing or Covid-19
vaccination requirements during the pandemic.
Kennedy did not provide specific examples or identify the reports he cited, but
he said Germany was “targeting physicians who put their patients first” and was
“punishing citizens for making their own medical choices.”
He accused Berlin of undermining the doctor–patient relationship and replacing
it with “a dangerous system that makes physicians enforcers of state policies.”
Former German Health Minister Karl Lauterbach also pushed back on the claims,
telling Kennedy on X to “take care of health problems in his own country.”
President Donald Trump on Wednesday declared he would ask Congress for a $1.5
trillion defense budget in 2027, a massive $500 billion increase from this
year’s Pentagon budget.
The huge boost likely reflects how expensive some of Trump’s military ambitions
are, from the Golden Dome air defense effort to his call for a new battleship
design. Neither of those programs could be fully funded under current spending
levels.
The president provided few details in his post on Truth Social, other than to
say the money would pay for his “Dream Military.” Trump did suggest that tariff
revenues could cover the increase, but even if he managed to circumvent
Congress’ constitutionally mandated power over spending, existing tariff
collections would still be several hundred billion short of what the president
plans to ask for.
While finding half-a-trillion dollars in new spending would prove difficult,
Trump and some congressional Republicans appeared confident they could do so.
The budget reached $1 trillion this year thanks to $150 billion in new money
Congress voted to pour into Pentagon coffers via a reconciliation bill, although
much of that will be spread out over the next five years on various long-term
projects.
Lawmakers have yet to complete a defense spending bill for this fiscal year,
although a final agreement is expected to increase Trump’s budget request by
several billion dollars.
Some Republicans have long argued for significant annual increases in Pentagon
funding, with a topline total of around 5 percent of GDP, up from the current
3.5 percent.
Rep. Don Bacon (R-Neb.) called Trump’s aspirations “a good news story” after his
administration proposed budgets defense hawks on Capitol Hill saw as lacking.
“We think we need a permanent 4 percent [of GDP] or better,” Bacon said. “That’s
what it’s gonna take to build our Navy, our Air Force, our ICBMs, our bombers,
and take care of our troops.”
The 2026 budget only reached $1 trillion due to the $150 billion added on by
Congress. That one-time infusion gave a boost to Golden Dome as well as new
initiatives to build more precision-guided munitions and air defense weapons.
But the funding will need to be included in year-on-year spending legislation,
something Trump’s new proposal appears to take into account.
Trump’s surprise budget announcement came just hours after he sent defense
stocks plunging by railing against the performance of major defense companies.
In another social media post, Trump said he would not allow defense companies to
buy back their own stocks, offer executives large salaries and issue dividends
to shareholders. He also slammed the companies for moving too slowly, and
charging too much, for weapons.
“A lot of us are saying we want a commitment to a sustained spending [increase],
not just a one-year,” Bacon said.
The White House and Republicans have left open the possibility of another
party-line megabill that could be used to increase defense spending again this
year. It is unclear if GOP leaders are willing to pursue the procedurally and
politically arduous approach again while they still maintain control of both
chambers of Congress.
Republicans would need to use that process again to accommodate even a portion
of Trump’s request because Democrats are likely to balk at any move that slashes
healthcare benefits, education and foreign aid in the ways Republicans have
sought, said one defense lobbyist.
“Golden Dome and Golden Fleet are completely unaffordable without budgets of
this size, so the administration would need to come up with the numbers to back
it up,” said the lobbyist, who was granted anonymity to discuss sensitive
spending dynamics. “But my guess is that the extra money will have to be in
reconciliation.”
House Appropriations Chair Tom Cole (R-Okla.) said overall defense spending
“needs to go up,” but wouldn’t say if the massive increase pitched by Trump is
realistic.
“I’ll take any request the president makes seriously, and we’ll see,” Cole said.
Another senior House appropriator, Rep. Steve Womack (R-Ark.), hailed Trump as
“absolutely right” in his own post.
“For too long, we have underfunded our defense apparatus—undermining our
national security and benefiting our foreign adversaries,” Womack said. “A
strong national defense is critical to our long‑term prosperity and to
protecting our country against every emerging threat. I commend President Trump
for his leadership and look forward to working to advance a $1.5 trillion
defense bill.”
Disclaimer
POLITICAL ADVERTISEMENT
* This is sponsored content from AstraZeneca.
* The advertisement is linked to public policy debates on the future of cancer
care in the EU.
More information here.
Europe has made huge strides in the fight against cancer.[1] Survival rates have
climbed, detection has improved and the continent has become home to some of the
world’s most respected research hubs.[2],[3] None of that progress came easy —
it was built on years of political attention and cooperation across borders.
However, as we look to 2026 and beyond, that progress stands at a crossroads.
Budget pressures and tougher global competition threaten to push cancer and
health care down the EU agenda. Europe’s Beating Cancer Plan — a flagship
initiative aimed at expanding screening, improving early detection and boosting
collaboration — is set to expire in 2027, with no clear plan to secure or extend
its gains.[4],[5]
“My [hope is that we can continue] the work started with Europe’s Beating Cancer
Plan and make it sustainable… [and] build on the lessons learned, [for other
disease areas] ” says Antonella Cardone, CEO of Cancer Patients Europe.
A new era in cancer treatment
Concern about the lapsing initiative is compounded by two significant shifts in
health care: declining investment and increasing scientific advancement.
Firstly, Europe has seen the increased adoption of cost-containment policies by
some member states. Under-investment in Europe in cancer medicines has been a
challenge — specifically with late and uneven funding, and at lower levels than
international peers such as the US — potentially leaving patients with slower
and more limited access to life-saving therapies.[6],[7],[8] Meanwhile, the
U.S., which pays on average double for medicines per capita than the EU,[9] is
actively working to rebalance its relationship with pharmaceuticals to secure
better pricing (“fair market value”) through policies across consecutive
administrations.[10] All the while, China is rapidly scaling investment in
biotech and clinical research, determined to capture the trials, talent, and
capital that once flowed naturally to Europe.[11]
The rebalancing of health and life-science investment can have significant
consequences. If Europe does not stay attractive for life-sciences investment,
the impact will extend beyond cancer patient outcomes. Jobs, tax revenues,
advanced manufacturing, and Europe’s leadership in strategic industries are all
at stake.[12]
Secondly, medical science has never looked more promising.[7] Artificial
intelligence is accelerating drug discovery, clinical trials, and diagnostics,
and the number of approved medicines for patients across Europe has jumped from
an average of one per year between 1995 and 2000 to 14 per year between 2021 and
2024.[13],[14],[15], [7] Digital health tools and innovative medtech startups
are multiplying, increasing competitiveness and lowering costs — guiding care
toward a future that is more personalized and precise.[16],[17]
Europe stands at the threshold of a new era in cancer treatment. But if
policymakers ease up now, progress could stall — and other regions, especially
the U.S. and China, are more than ready to widen the innovation gap.
Recognizing the strategic investment
Health spending is generally treated as a budget item to be contained. Yet
investment in cancer care has been one of Europe’s smartest economic
bets.[18],[19] The sector anchors millions of high-skilled jobs (it employs
around 29 million people in the EU[11]) and attracts global life sciences
investment. According to the European Commission, the sector contributes nearly
€1.5 trillion to the EU economy.[12] Studies from the Institute of Health
Economics confirm that money put into research directly translates into better
survival outcomes.[20]
The same report shows that although the overall spend on cancer is increasing,
the cost per patient has actually decreased since 1995, suggesting that
innovative treatments are increasing efficiency.[20]
Those gains matter not only to patients and families, but to Europe’s long-term
stability: healthier populations mean fewer costs down the line, stronger
productivity, and more sustainable public finances.[20]
Fixing Europe’s access gap
Cancer medicines bring transformative value — to patients, to society and to the
wider economy. [21]
However, even as oncology therapies advance, patients across Europe are not
benefiting equally. EFPIA’s 2024 Patients W.A.I.T. indicator shows that, on
average, just 46 percent of innovative medicines approved between 2020 and 2023
were available to patients in 2024.[22] On average, it takes 578 days for a new
oncology medicine to reach European patients, and only 29 percent of drugs are
fully available in all member states.[23]
This is not caused by a lack of breakthrough medicines, but by national policy
mechanisms that undervalue innovation. OECD and the Institute for Health
Economics data show that divergent HTA requirements, rigid cost-effectiveness
thresholds, price-volume clawbacks, ad hoc taxes on pharmaceutical revenues and
slow national reimbursement decisions collectively suppress timely access to new
cancer medicines across the EU.[24]
These disparities cut against Europe’s long-standing reputation as a collection
of societies that values equitable, high-quality care for all of its citizens.
It risks eroding one of the EU’s defining strengths: the commitment to fairness
and collective progress.
Cancer policy solutions for the EU
Although this is ultimately a matter for member states, embedding cancer as a
permanent EU priority — backed by funding, coordination, and accountability —
could give national systems the incentives and strategic direction to buck these
trends. These actions will reassure pharmaceutical companies that Europe is
serious about attracting clinical trials and the launch of new medicines,
ensuring that its citizens, societies and economies enjoy the benefits this
brings.
Europe’s Beating Cancer Plan delivered progress, but its expiry presents a
pivotal moment. 2026 and beyond bring a significant opportunity for the EU to
build on this by ensuring that member states implement National Cancer Control
Plans and have clear targets and accountability on their national performance,
including on investment and access. To do this, EU policymakers should consider
three actions as an immediate priority with lasting impact:
* Embed cancer and investment within EU governance. Build it into the European
Semester on health with mandatory indicators, regular reviews, and
accountability frameworks to ensure continuity. This model worked well during
Covid-19 and should be adapted for non-communicable diseases starting with
cancer as a pilot.
* Secure stable and sufficient funding. The Multiannual Financial Framework
must ensure adequate funding for health and cancer to encourage coordinated
initiatives across member states.
* Strengthen EU-level coordination. Ensure that pan-EU structures such as the
Comprehensive Cancer Centres and Cancer Mission Hubs are adequately funded
and empowered.
These are the building blocks of a lasting European commitment to cancer. With
action, Europe can secure a sustainable foundation for patients, resilience and
continued scientific excellence.
--------------------------------------------------------------------------------
[1] European Commission, OECD/European Observatory on Health Systems and
Policies. 2023. State of Health in the EU: Synthesis Report 2023. Available at:
https://health.ec.europa.eu/system/files/2023-12/state_2023_synthesis-report_en.pdf
[Accessed December 2025]
[2] Efpia. 2025. Cancer care 2025: an overview of cancer outcomes data across
Europe. Available at:
https://www.efpia.eu/news-events/the-efpia-view/statements-press-releases/ihe-cancer-comparator-report-2025/
[Accessed December 2025]
[3] Cancer Core Europe. 2024. Cancer Core Europe: Advancing Cancer Care Through
Collaboration. Available at:
https://www.cancercoreeurope.eu/cce-advancing-cancer-care-collaboration/
[Accessed December 2025]
[4] European Commission. 2021. Europe’s Beating Cancer Plan. Available
at:https://health.ec.europa.eu/system/files/2022-02/eu_cancer-plan_en_0.pdf
[Accessed December 2025]
[5] European Parliament. 2025. Europe’s Beating Cancer Plan: Implementation
findings.
https://www.europarl.europa.eu/RegData/etudes/STUD/2025/765809/EPRS_STU(2025)765809_EN.pdf
[Accessed December 2025]
[6] Hofmarcher, T., et al. 2024. Access to Oncology Medicines in EU and OECD
Countries (OECD Health Working Papers, No.170). OECD Publishing. Available at:
https://www.oecd.org/content/dam/oecd/en/publications/reports/2024/09/access-to-oncology-medicines-in-eu-and-oecd-countries_6cf189fe/c263c014-en.pdf
[Accessed December 2025]
[7] Manzano, A., et al. 2025. Comparator Report on Cancer in Europe 2025 –
Disease Burden, Costs and Access to Medicines and Molecular Diagnostics (IHE).
Available at: https://ihe.se/app/uploads/2025/03/IHE-REPORT-2025_2_.pdf
[Accessed December 2025]
[8] Efpia. [no date]. Europe’s choice. Available at:
https://www.efpia.eu/europes-choice/ [Accessed December 2025]
[9] OECD. 2024. Prescription Drug Expenditure per Capita.
https://data-explorer.oecd.org/vis?lc=en&pg=0&snb=1&vw=tb&df[ds]=dsDisseminateFinalDMZ&df[id]=DSD_SHA%40DF_SHA&df[ag]=OECD.ELS.HD&df[vs]=&pd=2015%2C&dq=.A.EXP_HEALTH.USD_PPP_PS%2BPT_EXP_HLTH._T..HC51%2BHC3.._T…&to[TIME_PERIOD]=false&lb=bt
[Accessed December 2025]
[10] The White House. 2025. Delivering most favored-nation prescription drug
pricing to American patients. Available at:
https://www.whitehouse.gov/presidential-actions/2025/05/delivering-most-favored-nation-prescription-drug-pricing-to-american-patients/
[Accessed December 2025]
[11] Eleanor Olcott, Haohsiang Ko and William Sandlund. 2025. The relentless
rise of China’s Biotechs. Financial Times. Available at:
https://www.ft.com/content/c0a1b15b-84ee-4549-85eb-ed3341112ce5 [Accessed
December 2025]
[12] European Commission, Directorate-General for Communication. 2025. Making
Europe a Global Leader in Life Sciences. Available at:
https://commission.europa.eu/news-and-media/news/making-europe-global-leader-life-sciences-2025-07-02_en
[Accessed December 2025]
[13] Financial Times. 2025. How AI is reshaping drug discovery. Available at:
https://www.ft.com/content/8c8f3c10-9c26-4e27-bc1a-b7c3defb3d95 [Accessed
December 2025]
[14] Seedblink. 2025. Europe’s HealthTech investment landscape in 2025: A deep
dive.
https://seedblink.com/blog/2025-05-30-europes-healthtech-investment-landscape-in-2025-a-deep-dive
[15] European Commission. [No date]. Artificial Intelligence in healthcare.
Available at:
https://health.ec.europa.eu/ehealth-digital-health-and-care/artificial-intelligence-healthcare_en
[Accessed December 2025]
[16] Codina, O. 2025. Code meets care: 20 European HealthTech startups to watch
in 2025 and beyond. EU-Startups. Available at:
https://www.eu-startups.com/2025/06/code-meets-care-20-european-healthtech-startups-to-watch-in-2025-and-beyond
[Accessed December 2025]
[17] Protogiros et al. 2025. Achieving digital transformation in cancer care
across Europe: Practical recommendations from the TRANSiTION project. Journal of
Cancer Policy. Available at:
https://www.sciencedirect.com/science/article/pii/S2213538325000281 [Accessed
December 2025]
[18] R-Health Consult. [no date]. The case for investing in a healthier future
for the European Union. EFPIA. Available at:
https://www.efpia.eu/media/xpkbiap5/the-case-for-investing-in-a-healthier-future-for-the-european-union.pdf
[Accessed December 2025]
[19] Pousette A., Hofmarcher T. 2024.Tackling inequalities in cancer care in the
European Union. Available at:
https://ihe.se/en/rapport/tackling-inequalities-in-cancer-care-in-the-european-union-2/
[Accessed December 2025]
[20] Efpia. 2025. Comparator Report Cancer in Europe 2025. Available at:
https://www.efpia.eu/media/0fbdi3hh/infographic-comparator-report-cancer-in-europe.pdf
[Accessed December 2025]
[21] Garau, E. et al. 2025. The Transformative Value of Cancer Medicines in
Europe. Dolon Ltd. Available at:
https://dolon.com/wp-content/uploads/2025/09/EOP_Investment-Value-of-Oncology-Medicines-White-Paper_2025-09-19-vF.pdf?x16809
[Accessed December 2025]
[22] IQVIA. 2025. EFPIA Patients W.A.I.T. Indicator 2024 Survey. Available at:
https://www.efpia.eu/media/oeganukm/efpia-patients-wait-indicator-2024-final-110425.pdf
[Accessed December 2025]
[23] Visentin M. 2025. Improving equitable access to medicines in Europe must
remain a priority. The Parliament. Available at:
https://www.theparliamentmagazine.eu/partner/article/improving-equitable-access-to-medicines-in-europe-must-remain-a-priority
[Accessed December 2025]
[24] Hofmarcher, T. et al. 2025. Access to novel cancer medicines in Europe:
inequities across countries and their drivers. ESMO Open. Available at:
https://www.esmoopen.com/action/showPdf?pii=S2059-7029%2825%2901679-5 [Accessed
December 2025]
PARIS — French lawmakers formally approved the country’s 2026 social security
budget on Tuesday, handing Prime Minister Sébastien Lecornu an important
political victory and offering some optimism to skittish markets worried France
isn’t serious about getting its public finances in check.
The bill, which covers state health care and pensions spending, was expected to
pass after having already been approved by the National Assembly, France’s more
powerful lower legislative chamber, last week, but its rejection by the Senate
over the weekend forced another vote.
The conservative Senate rejected the measure in part over concerns the
legislation does not sufficiently bring down the budget deficit. As part of a
compromise to ensure his government’s survival, Lecornu approved a measure in
the law that suspends until 2027 the controversial law passed in 2023 that
raised the retirement age for most workers from 62 to 64.
The government now faces the more arduous task of passing a state budget for
next year, which is a separate piece of legislation. The National Assembly’s
first attempt to pass a state budget ended with all but one MP voting against
the bill, which MPs had saddled with untenable and sometimes conflicting
amendments.
Lawmakers from both branches of parliament will on Friday attempt to forge a
compromise text during a U.S.-style conference committee in what one National
Assembly official described as a “make or break” moment.
France is highly unlikely to face a government shutdown similar to what happened
in the United States earlier this year as lawmakers can approve a measure
carrying the 2025 budget over into next year. But such a stopgap would
exacerbate the worrying financial outlook in the European Union’s second-largest
economy.
France’s current fiscal plans for 2026 are now projected to carry a budget
deficit to 5.3 percent of gross domestic product, significantly higher than the
4.7 percent of GDP deficit initially proposed by the government and welcomed by
the European Commission.
Lecornu said in October that whatever fiscal plans lawmakers agree on should not
carry a budget deficit for 2026 that exceeds 5 percent of GDP.
This article is presented by EFPIA with the support of AbbVie
I made a trip back to Europe recently, where I spent the vast majority of my
pharmaceutical career, to share my perspectives on competitiveness at the
European Health Summit. Now that I work in a role responsible for supporting
patient access to medicine globally, I view Europe, and how it compares
internationally, through a new lens, and I have been reflecting further on why
the choices made today will have such a critical impact on where medicines are
developed tomorrow.
Today, many patients around the world benefit from medicines built on European
science and breakthroughs of the last 20 years. Europeans, like me, can be proud
of this contribution. As I look forward, my concern is that we may not be able
to make the same claim in the next 20 years. It’s clear that Europe has a
choice. Investing in sustainable medicines growth and other enabling policies
will, I believe, bring significant benefits. Not doing so risks diminishing
global influence.
> Today, many patients around the world benefit from medicines built on European
> science and breakthroughs of the last 20 years
I reflect on three important points: 1) investment in healthcare benefits
individuals, healthcare and society, but the scale of this benefit remains
underappreciated; 2) connected to this, the underpinning science for future
innovation is increasingly happening elsewhere; and 3) this means the choices we
make today must address both of these trends.
First, let’s use the example of migraine. As I have heard a patient say,
“Migraine will not kill you but neither [will they] let you live.”[1]
Individuals can face being under a migraine attack for more than half of every
month, unable to leave home, maintain a job and engage in society.[2] It is the
second biggest cause of disability globally and the first among young women.[3]
It affects the quality of life of millions of Europeans.[4] From 2011-21 the
economic burden of migraine in Europe due to the loss of working days ranged
from €35-557 billion, depending on the country, representing 1-2 percent of
gross domestic product (GDP).[5]
Overall socioeconomic burden of migraine as percentage of the country’s GDP in
2021
Source: WifOR, The socioeconomic burden of migraine. The case of 6 European
Countries.5
Access to effective therapies could radically improve individuals’ lives and
their ability to return to work.[6] Yet, despite the staggering economic and
personal impacts, in some member states the latest medicines are either not
reimbursed or only available after several treatment failures.[7] Imagine if
Europe shifted its perspective on these conditions, investing to improve not
only health but unlocking the potential for workforce and economic productivity?
Moving to my second point, against this backdrop of underinvestment, where are
scientific advances now happening in our sector?
In recent years it is impressive to see China has become the second-largest drug
developer in the world,[8] and within five years it may lead the innovative
antibodies therapeutics sector,[9] which is particularly promising for complex
areas like oncology.
Cancer is projected to become the leading cause of death in Europe by 2035,[10]
yet the continent’s share of the number of oncology trials dropped from 41
percent in 2013 to 21 percent in 2023.10
Today, antibody-drug conjugates are bringing new hope in hard-to-treat tumor
types,[11] like ovarian,[12] lung[13] and colorectal[14] cancer, and we hope to
see more of these advances in the future. Unfortunately, Europe is no longer at
the forefront of the development of these innovations. This geographical shift
could impact high-quality jobs, the vitality of Europe’s biotech sector and,
most importantly, patients’ outcomes. [15]
> This is why I encourage choices to be made that clearly signal the value
> Europe attaches to medicines
This is why I encourage choices to be made that clearly signal the value Europe
attaches to medicines. This can be done by removing national cost-containment
measures, like clawbacks, that are increasingly eroding the ability of companies
to invest in European R&D. To provide a sense of their impact, between 2012 and
2023, clawbacks and price controls reduced manufacturer revenues by over €1.2
billion across five major EU markets, corresponding to a loss of 4.7 percent in
countries like Spain.[16] Moreover, we should address health technology
assessment approaches in Europe, or mandatory discount policies, which are
simply not adequately accounting for the wider societal value of medicines, such
as in the migraine example, and promoting a short-term approach to investment.
By broadening horizons and choosing a long-term investment strategy for
medicines and the life science sector, Europe will not only enable this
strategic industry to drive global competitiveness but, more importantly, bring
hope to Europeans suffering from health conditions.
AbbVie SA/NV – BE-ABBV-250177 (V1.0) – December 2025
--------------------------------------------------------------------------------
[1] The Parliament Magazine,
https://www.theparliamentmagazine.eu/partner/article/unmet-medical-needs-and-migraine-assessing-the-added-value-for-patients-and-society,
Last accessed December 2025.
[2] The Migraine Trust;
https://migrainetrust.org/understand-migraine/types-of-migraine/chronic-migraine/,
Last accessed December 2025.
[3] Steiner TJ, et al; Lifting The Burden: the Global Campaign against Headache.
Migraine remains second among the world’s causes of disability, and first among
young women: findings from GBD2019. J Headache Pain. 2020 Dec 2;21(1):137
[4] Coppola G, Brown JD, Mercadante AR, Drakeley S, Sternbach N, Jenkins A,
Blakeman KH, Gendolla A. The epidemiology and unmet need of migraine in five
european countries: results from the national health and wellness survey. BMC
Public Health. 2025 Jan 21;25(1):254. doi: 10.1186/s12889-024-21244-8.
[5] WifOR. Calculating the Socioeconomic Burden of Migraine: The Case of 6
European Countries. Available at:
[https://www.wifor.com/en/download/the-socioeconomic-burden-of-migraine-the-case-of-6-european-countries/?wpdmdl=358249&refresh=687823f915e751752703993].
Accessed June 2025.
[6] Seddik AH, Schiener C, Ostwald DA, Schramm S, Huels J, Katsarava Z. Social
Impact of Prophylactic Migraine Treatments in Germany: A State-Transition and
Open Cohort Approach. Value Health. 2021 Oct;24(10):1446-1453. doi:
10.1016/j.jval.2021.04.1281
[7] Moisset X, Demarquay G, et al., Migraine treatment: Position paper of the
French Headache Society. Rev Neurol (Paris). 2024 Dec;180(10):1087-1099. doi:
10.1016/j.neurol.2024.09.008.
[8] The Economist,
https://www.economist.com/china/2025/11/23/chinese-pharma-is-on-the-cusp-of-going-global,
Last accessed December 2025.
[9] Crescioli S, Reichert JM. Innovative antibody therapeutic development in
China compared with the USA and Europe. Nat Rev Drug Discov. Published online
November 7, 2025.
[10] Manzano A., Svedman C., Hofmarcher T., Wilking N.. Comparator Report on
Cancer in Europe 2025 – Disease Burden, Costs and Access to Medicines and
Molecular Diagnostics. EFPIA, 2025. [IHE REPORT 2025:2, page 20]
[11] Armstrong GB, Graham H, Cheung A, Montaseri H, Burley GA, Karagiannis SN,
Rattray Z. Antibody-drug conjugates as multimodal therapies against
hard-to-treat cancers. Adv Drug Deliv Rev. 2025 Sep;224:115648. doi:
10.1016/j.addr.2025.115648. Epub 2025 Jul 11. PMID: 40653109..
[12] Narayana, R.V.L., Gupta, R. Exploring the therapeutic use and outcome of
antibody-drug conjugates in ovarian cancer treatment. Oncogene 44, 2343–2356
(2025). https://doi.org/10.1038/s41388-025-03448-3
[13] Coleman, N., Yap, T.A., Heymach, J.V. et al. Antibody-drug conjugates in
lung cancer: dawn of a new era?. npj Precis. Onc. 7, 5 (2023).
https://doi.org/10.1038/s41698-022-00338-9
[14] Wang Y, Lu K, Xu Y, Xu S, Chu H, Fang X. Antibody-drug conjugates as
immuno-oncology agents in colorectal cancer: targets, payloads, and therapeutic
synergies. Front Immunol. 2025 Nov 3;16:1678907. doi:
10.3389/fimmu.2025.1678907. PMID: 41256852; PMCID: PMC12620403.
[15] EFPIA, Improving EU Clinical Trials: Proposals to Overcome Current
Challenges and Strengthen the Ecosystem,
efpias-list-of-proposals-clinical-trials-15-apr-2025.pdf, Last accessed December
2025.
[16] The EU General Pharmaceutical Legislation & Clawbacks, © Vital
Transformation BVBA, 2024.